Problems Relating to Surgical Operations, 1901; Blood Pressure
in Surgery, 1903; Hemorrhage and Transfusion, 1909;
Anemia and Resuscitation, 1914; and Anoci-association, 1914
(with Dr. W. E. Lower).


In the first of these addresses, the Ether Day Address, delivered at
the Massachusetts General Hospital in October, 1910, I first
enunciated the Kinetic Theory of Shock, the key to which was found
in laboratory researches and in a study of Darwin's "Expression
of the Emotions in Man and in Animals," whereby the phylogenetic
origin of the emotions was made manifest and the pathologic
identity of surgical and emotional shock was established.
Since 1910 my associates and I have continued our researches through--
(a) Histologic studies of all the organs and tissues of the body;
(b) Estimation of the H-ion concentration of the blood in the emotions
of anger and fear and after the application of many other forms of stimuli;
(c) Functional tests of the adrenals, and (d) Clinical observations.

It would seem that if the striking changes produced by fear
and anger and by physical trauma in the master organ of the body--
the brain--were due to WORK, then we should expect to find
corresponding histologic changes in other organs of the body as well.
We therefore examined every organ and tissue of the bodies of animals
which had been subjected to intense fear and anger and to infection and
to the action of foreign proteins, some animals being killed immediately;
some several hours after the immediate effects of the stimuli had passed;
some after seances of strong emotion had been repeated several
times during a week or longer.