In the Ether Day Address the phylogenetic key supplied by Darwin was
utilized to formulate the principle that the organism reacts as a unit
to the stimuli of physical injury, of emotion, of infection, etc.
To the study of these reactions (transformations of energy)
the epoch-making work of Sherrington, "The Integrative Action
of the Nervous System," gave an added key by which the dominating
role of the brain was determined. Later the original work
of Cannon on the adrenal glands gave facts, and an experimental
method by which Darwin's phylogenetic theory of the emotions
was further elaborated in other papers, especially in the one
entitled "Phylogenetic Association in Relation to the Emotions,"
read before The American Philosophical Society in April, 1911.
GEORGE W. CRILE. CLEVELAND, OHIO, _February, 1915_.



CONTENTS PAGE PHYLOGENETIC ASSOCIATION IN RELATION TO CERTAIN MEDICAL
PROBLEMS. . . . . . . . . . . . . . . . . . . . . . . . . . .1

PHYLOGENETIC ASSOCIATION IN RELATION TO THE EMOTIONS . . . .
55 PAIN, LAUGHTER, AND CRYING. . . . . . . . . . . . . . . . . 77

THE RELATION BETWEEN THE PHYSICAL STATE OF THE BRAIN-CELLS AND
BRAIN FUNCTIONS-EXPERIMENTAL AND CLINICAL . . . .111

A MECHANISTIC VIEW OF PSYCHOLOGY . . . . . . . . . . . . . .127

A MECHANISTIC THEORY OF DISEASE. . . . . . . . . . . . . . .157