In two cases, though no nasal symptoms developed, about two weeks
after the calculated onset, slight symptoms of asthma made their
appearance. However, I could easily suppress them at this time with
the aid of the hand atomizer and ozonizer, a very ingenious little
apparatus, of which I gave a thorough description in my last year's
article. I used the ozone inhalations every four hours, in connection
with the internal administration of the following prescription:

Rx Iodide of ammonia, 8;
Fl. ex. quebracho, 30;
Fl. ex. grindelia robusta, 15;
Tr. lobelia, 12;
Tr. belladonna, 8;
Syr. pruni, virg., q.s., ad 120.

Sig.--Teaspoonful three or more times during twenty-four hours.

However, toward the end of the fourth week, especially in one case--a
stout, heavy-set gentleman--very grave asthmatic symptoms developed,
which compelled me to apply Chapman's spinal ice bag, as well as
resort to the internal administration of large doses of codeine during
the paroxysm, with the most beneficial result.

I gave also oxygen inhalations a fair trial in the two cases. I find
them to act very soothingly in the simple asthma, facilitating
respiration after a few minutes; but during the paroxysmal stage they
cannot be utilized, for the reason that respiration is short and
rapid, and does not permit of a control in the quantity of the gas to
be inhaled. Consequently, it is either of little use as a remedy; or,
if too much is taken, a disagreeable headache will be the consequence.