of the Dukes of Brittany became extinct; and the hand of the heiress,
Anne of Brittany, a girl of twelve, attracted many suitors. It was
clearly a matter of supreme importance to the King of France that this
important territory should not pass by marriage into the hands of an
enemy. The Bretons, on the other hand, clung to their independence and
dreaded absorption in the unifying French state. After many intrigues
her council advised the young duchess to accept Maximilian as her
husband, and she was married to him by proxy in March, 1490. Charles
VIII immediately entered Brittany at the head of a strong force and,
despite a fierce and prolonged resistance, conquered the country, and
gained possession of Anne's person (August, 1491). The temptation was
too strong to be resisted. Margaret, after residing in France as his
affianced wife for eight years, was repudiated and finally, two years
later, sent back to the Netherlands, while Anne was compelled to break
off her marriage with Margaret's father, and became Charles' queen. This
double slight was never forgiven either by Maximilian or by Margaret,
and was the direct cause of the negotiations for the double Spanish
marriage, which, though delayed by the suspicious caution of the two
chief negotiators, Ferdinand and Maximilian, was at length arranged. In
August, 1496, an imposing fleet conveyed the Infanta Juana to Antwerp
and she was married to Philip at Lille. In the following April Margaret
and Don Juan were wedded in the cathedral of Burgos. The union was
followed by a series of catastrophes in the Spanish royal family. While
on his way with his wife to attend the marriage of his older sister
Isabel with the King of Portugal, Juan caught a malignant fever and
expired at Salamanca in October, 1497.

The newly-married Queen of Portugal now became the heiress to the crowns
of Aragon and Castile, but she died a year later and shortly afterwards
her infant son. The succession therefore passed to the younger sister,