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Autobiography, Letters and Literary Remains of Mrs. Piozzi (Thrale) (2nd ed.) (2 vols.) - Edited with notes and Introductory Account of her life and writings by Hester Lynch Piozzi
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afterwards twitted by Mrs. Thrale with irregularity, he replied,
"Madam, I do not like to come down to vacuity."

[Footnote 1: Dr. Burney states that in 1765 "he very frequently met
Johnson at Streatham, where they had many long conversations, after
sitting up as long as the fire and candles lasted, and much longer
than the patience of the servants subsisted."]

He was subject to dreadful fits of depression, caused or accompanied
by compunction for venial or fancied sins, by the fear of death or
madness--(the only things he did fear), and by ingrained ineradicable
disease. When Boswell speaks of his "striving against evil," "Ay,"
she writes in the margin, "and against the King's evil."

If his early familiarity with all the miseries of destitution,
aggravated by disease, had increased his natural roughness and
irritability, on the other hand it had helped largely to bring out
his sterling virtues,--his discriminating charity, his genuine
benevolence, his well-timed generosity, his large-hearted sympathy
with real suffering. But he required it to be material and positive,
and scoffed at mere mental or sentimental woes. "The sight of people
who want food and raiment is so common in great cities, that a surly
fellow like me has no compassion to spare for wounds given only to
vanity or softness." He said it was enough to make a plain man sick
to hear pity lavished on a family reduced by losses to exchange a
fine house for a snug cottage; and when condolence was demanded for a
lady of rank in mourning for a baby, he contrasted her with a
washerwoman with half-a-dozen children dependent on her daily labour
for their daily bread.[1]

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