much so that at times it is almost impossible for him to walk erect. He
experiences an insatiable desire for sleep, and yet upon retiring he
lies awake for hours, tormented by his troubled reflections, and at last
falls into an uneasy slumber, of short duration, disturbed by wretched
dreams.

+Hard, red pimples+ frequently appear on the face, forehead and body,
+scaly patches+ round the +ears, eyes, nose and lips+, a +black or
bluish semi-circle+ shows itself under the +eyes+, and there is a hollow
mark from the corner of the eye in a slanting direction under the
cheekbone to the angle of the mouth, which tells its tale. The +skin is
livid and clammy+ and the digestion is bad. The patient is tormented
with +flatulency+, which he cannot always control and which he justly
dreads, as it renders him an object of +disgust+ to all in his presence.
The bowels are generally +constipated+, obliging him to strain much at
stool, thus aggravating the irritation of the prostate gland vesiculæ
seminales and increasing the +seminal losses+.

The bladder is irritable and will retain the urine but a short time; the
ureters and kidneys are also inflamed and in post-mortem examinations
are sometimes found to contain +abscesses+; they are the seat of much
pain when pressure is made over the intervertebral spaces of the dorsal
and lumbar vertebræ or backbone. The vesiculæ seminales have +been
indurated+ and can be felt to be +knotty+ and +hard+. The spinal marrow
is very sensitive throughout its whole extent; the cerebellum is the
seat of a +dull+ and +heavy pain+, and there is a feeling of pressure
upon the brain. Cerebral congestion now and then occurs. This stage of
the disease is frequently accompanied by +Bronchitis+ or a continued
+Catarrh+, also by disease of the +rectum+ and all the +tissues near
the generative organs+.