Scientific American Supplement, No. 324, March 18, 1882 by Various
page 73 of 143 (51%)
page 73 of 143 (51%)
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trimethyl-hydrethylene-ammonium.]
The fusing point of atropine is not 194 deg. F., as stated by Planta, but 237 deg. F. Crystallized from not too dilute alcohol it forms crystals which are aggregations of prisms. Toluene, alcohol, and chloroform all dissolve atropine readily. Its double gold salt is very characteristic. It is generally precipitated in the form of an oil which solidifies rapidly and may be crystallized from hot water after the addition of a little hydrochloric acid. This clouds in cooling, and after a certain time it separates in small crystals of indeterminate form which unite in warty concretions. After drying the salt forms a dull powder, melting between 275 deg. F. and 280 deg. F. It also melts in boiling water, and its aqueous solution exposed to the light is partially reduced, 100 grammes of water acidulated with 10 cubic centimeters of 1.190 deg. solution of hydrochloric acid dissolves 0.137 gramme of the gold salt at 136 deg. F. to 140 deg. F. I should fancy that the above particulars are sufficent to completely differentiate atropine from all the other mydriatic alkaloids. II.--THE ATROPINE OF DATURA STRAMONIUM. Planta has already tried to show that atropine is identical with the daturine obtained by Geiger and Hesse, founding his opinion on facts which we nowadays look upon as doubtful. This identity was generally admitted by all chemists. The pharmacologists, headed by Soubeiran, Erhardt, Schroff, and Poehl, were much more reserved in their judgment. I thought it as well, therefore, to recommence the study of daturine, the more so as I had already determined the incorrectness of the |
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