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Hormones and Heredity by J. T. Cunningham
page 8 of 228 (03%)
male Cervidae, to one season of the year in which alone the sexual organs
are active. It had been known for centuries that the normal development of
male sexual characters did not take place in castrated animals, but the
exact nature of the influence of the male generative organs on that
development was not known till a year or two later than 1900, when it was
shown to be due to an internal secretion. My argument was that all
selection theories failed to account for the limitation of secondary
sexual characters in heredity, whereas the Lamarckian theory would explain
them if the assumption were made that the effects of stimulation having
been originally produced when the body and tissues were under the
influence of the sexual organs in functional activity, these effects were
only developed in heredity when the body was in the same condition.

About the year 1906, when preparing two special lectures in London
University on the same subject, I became acquainted with the work of
Starling and others on internal secretions or hormones, and saw at once
that the hormone from the testes was the actual agent which constituted
the 'influence' assumed by me in 1900. In these lectures I elaborated a
definite Lamarckian theory of the origin of Secondary Sexual Characters in
relation to Hormones, extending the theory also to ordinary adaptive
structures and characters which are not related to sex. Having met with
many obstacles in endeavouring to get a paper founded on the original
lectures published in England, I finally sent it to Professor Wilhelm
Roux, the editor of the _Archiv fuer Entwicklungsmechanik der Organismen_,
in which it was published in 1908.

In his volume on the Embryology of the Invertebrata, 1914 (_Text-Book of
Embryology_, edited by Walter Heape, vol. i.), Professor E. W. MacBride in
his general summary (chapter xviii.) puts forward suggestions concerning
hormones without any reference to those who have discussed the subject
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