strong and durable. The action, which is immediate and more intense
with the isolated principle, does not appear for some minutes after the
eating of oats; in both cases it increases to a certain point, then
diminishes and disappears. The total duration of the effect is stated to
be an hour per kilogramme of oats ingested.

* * * * *




FILARIA DISEASE.


The rapid strides which our knowledge has made during the past few years
in the subject of the filaria parasite have been mainly owing to the
diligent researches of Dr. Patrick Manson, who continues to work at the
question. In the last number of the _Medical Reports for China_, Dr.
Manson deals with the phenomenon known as "filarial periodicity," and
with the fate of embryo parasites not removed from the blood. The
intimate pathology of the disease, and the subject of abscess caused
by the death of the parent filaria, also receive further attention.
An endeavor to explain the phenomenon of "filarial periodicity" by an
appeal to the logical "method of concomitant variations" takes Manson
into an interesting excursion which is not productive of any positive
results; nor is any more certain conclusion come to with regard to the
fate of the embryos which disappear from the blood during the day time.
Manson does not incline to the view that there is a diurnal intermittent
reproduction of embryos with a corresponding destruction. An original
and important speculation is made with respect to the intimate pathology