sheep inoculated with the weak anthrax virus would be alive in
the anthrax-infected field, while those not so protected would
all be dead. A prediction verified is a conclusion
corroborated, an investigator encouraged.

Early in 1797, through another outbreak of cowpox, Jenner was
able to inoculate three persons with variola, only to find as
before that they were immune from smallpox. He now felt himself
justified in preparing a paper for the Royal Society, the
highest scientific tribunal in England. The council, however,
returned him his paper with the remark that in their opinion
the amount of evidence was not strong enough to warrant its
publication in the Transactions. Jenner was wise enough not to
be discouraged, and so in June, 1798, he published the paper
himself under the title, "Inquiry into the causes and effects
of the Variolae-Vacciniae, a disease discovered in some of the
western counties of England, particularly Gloucestershire, and
known by the name of cowpox." This historic pamphlet, which
ranks with the great classics of medicine, was dedicated to Dr.
O. H. Parry, of Bath. Later on the Royal Society was sagacious
enough to elect the very man whose paper it had previously
refused.

While in London attending to the publication of his pamphlet,
Dr. Jenner called on the great surgeon Mr. Cline, and left some
cowpox virus with him for trial. Cline inoculated a young
tubercular patient with vaccinia and later with smallpox in no
less than three places. In due time this patient did not show a
sign of smallpox. So impressed was Cline with this remarkable
result that he wrote to Jenner thus: "I think the substitution